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1

Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leucocytes through a common receptor

Arfilli, Valentina, Carnicelli, Domenica, Rocchi, Laura, Ricci, Francesca, Pagliaro, Pasqualepaolo, Tazzari, Pier Luigi, Brigotti, Maurizio

Journal:

Biochemical Journal

Year:

2010

Language:

english

File:

PDF, 508 KB

english, 2010

2

Flow cytometry detection of Shiga toxins in the blood from children with hemolytic uremic syndrome

Pier Luigi Tazzari, Francesca Ricci, Domenica Carnicelli, Alfredo Caprioli, Alberto E. Tozzi, Gianfranco Rizzoni, Roberto Conte, Maurizio Brigotti

Journal:

Cytometry Part B: Clinical Cytometry

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

3

Shiga-like toxin I is a polynucleotide:adenosine glycosidase

Luigi Barbieri, Paola Valbonesi, Maurizio Brigotti, Lucio Montanaro, Fiorenzo Stirpe, Simonetta Sperti

Journal:

Molecular Microbiology

Year:

1998

Language:

english

File:

PDF, 655 KB

english, 1998

4

Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer

L Montanaro, M Brigotti, J Clohessy, S Barbieri, C Ceccarelli, D Santini, M Taffurelli, M Calienni, J Teruya-Feldstein, D Trerè, PP Pandolfi, M Derenzini

Journal:

The Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 927 KB

english, 2006

5

10.1038/30588

Sperti, Simonetta, Stirpe, Fiorenzo, Brigotti, Maurizio

Journal:

Year:

1998

Language:

english

File:

PDF, 115 KB

english, 1998

6

Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress

Roberta R. Alfieri, Mara A. Bonelli, Andrea Cavazzoni, Maurizio Brigotti, Claudia Fumarola, Piero Sestili, Paola Mozzoni, Giuseppe De Palma, Antonio Mutti, Domenica Carnicelli, Federica Vacondio, Clau

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 261 KB

english, 2006

7

tRNATrp as cofactor of gelonin, a ribosome-inactivating protein with RNA-N-glycosidase activity features required for the cofactor activity

Maurizio Brigotti, Domenica Carnicelli, Paola Alvergna, Alessandra Pallanca, Simonetta Sperti, Lucio Montanaro

Journal:

Year:

1996

Language:

english

File:

PDF, 557 KB

english, 1996

8

The Interactions of Human Neutrophils with Shiga Toxins and Related Plant Toxins: Danger or Safety?

Brigotti, Maurizio

Journal:

Year:

2012

Language:

english

File:

PDF, 642 KB

english, 2012

9

Interaction of diphtheria toxin fragment A and of elongation factor 2 with Cibacron blue

Fioretta Rambelli, Maurizio Brigotti, Simonetta Sperti, Lucio Montanaro

Journal:

Bioscience Reports

Year:

1987

Language:

english

File:

PDF, 371 KB

english, 1987

10

Uncompetitive inhibition by adenine of the RNA-N-glycosidase activity of ribosome-inactivating proteins

Alessandra Pallanca, Raffaella Mazzaracchio, Maurizio Brigotti, Domenica Carnicelli, Paola Alvergna, Simonetta Sperti, Lucio Montanaro

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998

11

Elongation factor 2 from Artemia salina embryos and its affinity for ribosomes

Mariacristina ZAMBONI, Maurizio BRIGOTTI, Lucio MONTANARO, Simonetta SPERTI

Journal:

Year:

1991

Language:

english

File:

PDF, 722 KB

english, 1991

12

Attenuated Expression of 70-kDa Heat Shock Protein in WI-38 Human Fibroblasts during Aging in Vitro

Mara A. Bonelli, Roberta R. Alfieri, Pier Giorgio Petronini, Maurizio Brigotti, Cinzia Campanini, Angelo F. Borghetti

Journal:

Experimental Cell Research

Year:

1999

Language:

english

File:

PDF, 653 KB

english, 1999

13

Alpha-sarcin impairs the N-glycosidase activity of ricin on ribosomes

Simonetta Sperti, Mariacristina Zamboni, Maurizio Brigotti, Fioretta Rambelli, Lucio Montanaro

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 350 KB

english, 1989

14

Differential requirement of ATP and extra-ribosomal proteins for ribosome inactivation by eight RNA N-glycosidases

Domenica Carnicelli, Maurizio Brigotti, Lucio Montanaro, Simonetta Sperti

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 263 KB

english, 1992

15

Differential up-regulation by tRNAs of ribosome-inactivating proteins

Maurizio Brigotti, Domenica Carnicelli, Paola Alvergna, Alessandra Pallanca, Simonetta Sperti, Lucio Montanaro

Journal:

Year:

1995

Language:

english

File:

PDF, 372 KB

english, 1995

16

Partial purification of two proteins which sensitize ribosomes to gelonin: Sensitization is not linked to phosphorylation of ribosomal proteins

Maurizio Brigotti, Simonetta Sperti, Domenica Carnicelli, Lucio Montanaro

Journal:

Year:

1993

Language:

english

File:

PDF, 469 KB

english, 1993

17

Shiga toxin 1 acting on DNA in vitro is a heat-stable enzyme not requiring proteolytic activation

Maurizio Brigotti, Domenica Carnicelli, Antonio González Vara

Journal:

Year:

2004

Language:

english

File:

PDF, 229 KB

english, 2004

18

Inhibition by suramin of protein synthesis in vitro. Ribosomes as the target of the drug

Maurizio Brigotti, Roberta R. Alfieri, Pier Giorgio Petronini, Domenica Carnicelli

Journal:

Year:

2006

Language:

english

File:

PDF, 298 KB

english, 2006

19

Shiga toxin 1 and ricin inhibit the repair of H2O2-induced DNA single strand breaks in cultured mammalian cells

Piero Sestili, Roberta Alfieri, Domenica Carnicelli, Chiara Martinelli, Luigi Barbieri, Fiorenzo Stirpe, Mara Bonelli, Pier Giorgio Petronini, Maurizio Brigotti

Journal:

Year:

2005

Language:

english

File:

PDF, 235 KB

english, 2005

20

Ribosome-inactivating proteins depurinate poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase and have transforming activity for 3T3 fibroblasts

Luigi Barbieri, Maurizio Brigotti, Paolo Perocco, Domenica Carnicelli, Marialibera Ciani, Laura Mercatali, Fiorenzo Stirpe

Journal:

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

21

Identification of the tRNAs which up-regulate agrostin, barley RIP and PAP-S, three ribosome-inactivating proteins of plant origin

Maurizio Brigotti, Gérard Keith, Alessandra Pallanca, Domenica Carnicelli, Paola Alvergna, Guy Dirheimer, Lucio Montanaro, Simonetta Sperti

Journal:

Year:

1998

Language:

english

File:

PDF, 113 KB

english, 1998

22

A survey of adenine and 4-aminopyrazolo[3,4-d]pyrimidine (4-APP) as inhibitors of ribosome-inactivating proteins (RIPs)

Maurizio Brigotti, Simona Rizzi, Domenica Carnicelli, Lucio Montanaro, Simonetta Sperti

Journal:

Year:

2000

Language:

english

File:

PDF, 57 KB

english, 2000

23

Shiga toxin 1: damage to DNA in vitro

Maurizio Brigotti, Paola Accorsi, Domenica Carnicelli, Simona Rizzi, Antonio González Vara, Lucio Montanaro, Simonetta Sperti

Journal:

Year:

2001

Language:

english

File:

PDF, 247 KB

english, 2001

24

The RNA-N-glycosidase activity of Shiga-like toxin I: Kinetic parameters of the native and activated toxin

Maurizio Brigotti, Domenica Carnicelli, Paola Alvergna, Raffaella Mazzaracchio, Simonetta Sperti, Lucio Montanaro

Journal:

Year:

1997

Language:

english

File:

PDF, 585 KB

english, 1997

25

Primer tRNATrp of RSV-transformed or RAV-1-infected cells up-regulates the antiribosomal activity of gelonin

Maurizio Brigotti, Pier Giorgio Petronini, Angelo F. Borghetti, Guido G. Guidotti, Simonetta Sperti, Lucio Montanaro

Journal:

Year:

1998

Language:

english

File:

PDF, 743 KB

english, 1998

26

Nucleotides U28–A42 and A37 in unmodified yeast tRNATrp as negative identity elements for bovine tryptophanyl-tRNA synthetase

Domenica Carnicelli, Maurizio Brigotti, Simona Rizzi, Gérard Keith, Lucio Montanaro, Simonetta Sperti

Journal:

Year:

2001

Language:

english

File:

PDF, 116 KB

english, 2001

27

5′-Untranslated region of heat shock protein 70 mRNA drives translation under hypertonic conditions

Rocchi, Laura, Alfieri, Roberta R., Petronini, Pier Giorgio, Montanaro, Lorenzo, Brigotti, Maurizio

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 430 KB

english, 2013

28

Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells

Fiume, Luigi, Vettraino, Marina, Carnicelli, Domenica, Arfilli, Valentina, Di Stefano, Giuseppina, Brigotti, Maurizio

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 359 KB

english, 2013

29

The Influence of Hematological Parameters on Tumor Control and Survival in Lung SBRT

Brigotti, S., Stephans, K., Reddy, C.A., Djemil, T., Woody, N.M., Videtic, G.M.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

30

Identification of TLR4 as the Receptor That Recognizes Shiga Toxins in Human Neutrophils

Brigotti, M., Carnicelli, D., Arfilli, V., Tamassia, N., Borsetti, F., Fabbri, E., Tazzari, P. L., Ricci, F., Pagliaro, P., Spisni, E., Cassatella, M. A.

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

31

Novel Dyskerin-Mediated Mechanism of p53 Inactivation through Defective mRNA Translation

Montanaro, L., Calienni, M., Bertoni, S., Rocchi, L., Sansone, P., Storci, G., Santini, D., Ceccarelli, C., Taffurelli, M., Carnicelli, D., Brigotti, M., Bonafe, M., Trere, D., Derenzini, M.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 551 KB

english, 2010

32

Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells

Journal:

The FASEB Journal

Year:

2002

Language:

english

File:

PDF, 178 KB

english, 2002

33

Shiga Toxins Present in the Gut and in the Polymorphonuclear Leukocytes Circulating in the Blood of Children with Hemolytic-Uremic Syndrome

Brigotti, M., Caprioli, A., Tozzi, A. E., Tazzari, P. L., Ricci, F., Conte, R., Carnicelli, D., Procaccino, M. A., Minelli, F., Ferretti, A. V. S., Paglialonga, F., Edefonti, A., Rizzoni, G.

Journal:

Journal of Clinical Microbiology

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

34

Change in Conformation with Reduction of -Helix Content Causes Loss of Neutrophil Binding Activity in Fully Cytotoxic Shiga Toxin 1

Brigotti, M., Carnicelli, D., Arfilli, V., Rocchi, L., Ricci, F., Pagliaro, P., Tazzari, P. L., Vara, A. G., Amelia, M., Manoli, F., Monti, S.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

35

A rapid and sensitive method to measure the enzymatic activity of ribosome-inactivating proteins

Journal:

Nucleic Acids Research

Year:

1998

Language:

english

File:

PDF, 47 KB

english, 1998

36

4-Aminopyrazolo[3,4-d]pyrimidine (4-APP) as a novel inhibitor of the RNA and DNA depurination induced by Shiga toxin 1

Journal:

Nucleic Acids Research

Year:

2000

Language:

english

File:

PDF, 415 KB

english, 2000

37

Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration

Brigotti, M., Tazzari, P. L., Ravanelli, E., Carnicelli, D., Barbieri, S., Rocchi, L., Arfilli, V., Scavia, G., Ricci, F., Bontadini, A., Alfieri, R. R., Petronini, P. G., Pecoraro, C., Tozzi, A. E.,

Journal:

Journal of Leukocyte Biology

Year:

2010

Language:

english

File:

PDF, 979 KB

english, 2010

38

Interactions between Shiga toxins and human polymorphonuclear leukocytes

Brigotti, M., Carnicelli, D., Ravanelli, E., Barbieri, S., Ricci, F., Bontadini, A., Tozzi, A. E., Scavia, G., Caprioli, A., Tazzari, P. L.

Journal:

Journal of Leukocyte Biology

Year:

2008

Language:

english

File:

PDF, 700 KB

english, 2008

39

Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation

Rocchi, L., Pacilli, A., Sethi, R., Penzo, M., Schneider, R. J., Trere, D., Brigotti, M., Montanaro, L.

Journal:

Nucleic Acids Research

Year:

2013

Language:

english

File:

PDF, 4.06 MB

english, 2013

40

Shiga Toxin 1, as DNA Repair Inhibitor, Synergistically Potentiates the Activity of the Anticancer Drug, Mafosfamide, on Raji Cells

Brigotti, Maurizio, Arfilli, Valentina, Carnicelli, Domenica, Rocchi, Laura, Calcabrini, Cinzia, Ricci, Francesca, Pagliaro, Pasqualepaolo, Tazzari, Pier, Alfieri, Roberta, Petronini, Pier, Sestili, P

Journal:

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

41

Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation

Penzo, M., Rocchi, L., Brugiere, S., Carnicelli, D., Onofrillo, C., Coute, Y., Brigotti, M., Montanaro, L.

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

42

The Antibiotic Polymyxin B Impairs the Interactions between Shiga Toxins and Human Neutrophils

Carnicelli, D., Arfilli, V., Ricci, F., Velati, C., Tazzari, P. L., Brigotti, M.

Journal:

The Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 1.84 MB

english, 2016

43

RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes

Lauria, Fabio, Tebaldi, Toma, Lunelli, Lorenzo, Struffi, Paolo, Gatto, Pamela, Pugliese, Andrea, Brigotti, Maurizio, Montanaro, Lorenzo, Ciribilli, Yari, Inga, Alberto, Quattrone, Alessandro, Sanguine

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 2.82 MB

english, 2015

44

A reconstituted cell-free assay for the evaluation of the intrinsic activity of purified human ribosomes

Penzo, Marianna, Carnicelli, Domenica, Montanaro, Lorenzo, Brigotti, Maurizio

Journal:

Nature Protocols

Year:

2016

Language:

english

File:

PDF, 976 KB

english, 2016

45

Molecular Damage and Induction of Proinflammatory Cytokines in Human Endothelial Cells Exposed to Shiga Toxin 1, Shiga Toxin 2, and -Sarcin

Brigotti, M., Carnicelli, D., Ravanelli, E., Vara, A. G., Martinelli, C., Alfieri, R. R., Petronini, P. G., Sestili, P.

Journal:

Infection and Immunity

Year:

2007

Language:

english

File:

PDF, 217 KB

english, 2007

46

Serum Shiga toxin 2 values in patients during acute phase of diarrhoea-associated haemolytic uraemic syndrome

He, Xiaohua, Quiñones, Beatriz, Loo, Maroeska Te, Loos, Sebastian, Scavia, Gaia, Brigotti, Maurizio, Levtchenko, Elena, Monnens, Leo

Journal:

Acta Paediatrica

Year:

2015

Language:

english

File:

PDF, 125 KB

english, 2015

47

Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis

BRIGOTTI, Maurizio, PETRONINI, Pier Giorgio, CARNICELLI, Domenica, ALFIERI, Roberta R., BONELLI, Mara A., BORGHETTI, Angelo F., WHEELER, Kenneth P.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

48

Effect of α -sarcin and ribosome-inactivating proteins on the interaction of elongation factors with ribosomes

Brigotti, M, Rambelli, F, Zamboni, M, Montanaro, L, Sperti, S

Journal:

Biochemical Journal

Year:

1989

Language:

english

File:

PDF, 897 KB

english, 1989

49

High-pressure-liquid-chromatographic and fluorimetric methods for the determination of adenine released from ribosomes by ricin and gelonin

Zamboni, M, Brigotti, M, Rambelli, F, Montanaro, L, Sperti, S

Journal:

Biochemical Journal

Year:

1989

Language:

english

File:

PDF, 980 KB

english, 1989

50

Effect of the antibiotic purpuromycin on cell-free protein-synthesizing systems

Rambelli, F, Brigotti, M, Zamboni, M, Denaro, M, Montanaro, L, Sperti, S

Journal:

Biochemical Journal

Year:

1989

Language:

english

File:

PDF, 612 KB

english, 1989